Other & EmergingEmerging Evidence

Vip Peptide Therapy

Benefits, Side Effects, Cost & Protocols

Vasoactive intestinal peptide (VIP) is a 28-amino acid peptide hormone belonging to the glucagon/secretin superfamily. Produced in the gut, pancreas, and brain, VIP stimulates cardiac contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure, and relaxes smooth muscle.

ByChris Riley(CFA)&Alex Evans, PharmD, MBA(PharmD, MBA)|Updated May 19, 2026

Clinically Reviewed

Reviewed by Alex Evans, PharmD, MBA · Updated May 2026

Evidence-Based

Sourced from FDA, PubMed & ClinicalTrials.gov · View sources

FDA Status

FDA-approved drug

Evidence

Emerging Evidence

Who Is Vip Best For?

Gut functionNeuroprotectionImmune modulationPrimarily animal or early-phase data

How Vip Works

Binds to VPAC receptors with effects on smooth muscle relaxation, secretion, and neuroprotection.

Vip FAQ

What is VIP?

VIP (Vasoactive Intestinal Peptide) is a naturally occurring neuropeptide with wide-ranging effects on the gut, nervous system, and immune function.

How does VIP work?

Binds to VPAC receptors with effects on smooth muscle relaxation, secretion, and neuroprotection.

Is VIP legal to buy?

VIP is sold as a research chemical for laboratory use only. It is not approved for human use by the FDA. Regulations vary by jurisdiction.

Where can I buy VIP?

VIP is available as a research compound from verified online vendors. Always verify third-party testing before purchasing.

What category does VIP belong to?

VIP is primarily classified as a other & emerging peptide. Miscellaneous and emerging peptides with unique or developing research profiles.

What are the research benefits of VIP?

VIP has been studied for: Gut function, Neuroprotection, Immune modulation. Vasoactive intestinal peptide; multi-system effects.

Key Studies

41,820 total on PubMed0

A case of VIPoma

Case Series · Int J Obstet Anesth

Multidisciplinary management including electrolyte control and epidural analgesia successfully managed VIPoma in pregnant woman

Vasoactive Intestinal Peptide Promotes Corneal Allograft Survival

Satitpitakul V, Sun Z, Suri K et al

Am J PatholAnimal

VIP administration improves corneal allograft survival by preserving endothelial cell density

Biosynthesis and Function of VIP and Oxytocin: Mechanisms of C-terminal Amidation, Oxytocin Secretion and Transport

Yonekura H, Kato I, Yamamoto Y et al

Endocrinology

VIP regulates glycemic control and C-terminal amidation is essential for peptide hormone biological activity

The role of vasoactive intestinal peptide in pulmonary diseases

Zhong HL, Li PZ, Li D et al

Life Sci · Life Sci

Vip News

Marmoset superior colliculus: neuronal expression of somatostatin but not vasoactive intestinal peptide or neuropeptide Y - Frontiers

Frontiers · 5 months ago

VIP Peptide Erectile Dysfunction: What the Evidence Shows and Practical Considerations - Portal CNJ

Portal CNJ · 9 days ago

Vasoactive intestinal peptide blockade suppresses tumor growth by regulating macrophage polarization and function in CT26 tumor-bearing mice - Nature

Nature · 40 months ago

VIP Peptide Erectile Dysfunction: What the Evidence Shows and Practical Considerations - Portal CNJ

Portal CNJ · 9 days ago

Serum Vasoactive Intestinal Peptide as a Novel Biomarker for Low‐Voltage Areas in Patients With Atrial Fibrillation - American Heart Association Journals

American Heart Association Journals · 14 months ago

News aggregated via Google News. Inclusion does not imply endorsement.

Medical Disclaimer: The information on this page is for educational purposes only and does not constitute medical advice. Peptide therapies have not been evaluated by the FDA for most listed indications.All prices shown are estimates based on publicly available data and may not reflect current pricing — providers and brands set their own prices and can change them at any time. Always verify pricing directly with the provider before purchasing. Consult a licensed healthcare provider before starting any peptide protocol.

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