Growth Hormone SecretionModerate Evidence

CJC-1295 Peptide Therapy

Benefits, Side Effects, Cost & Protocols

CJC-1295 peptide molecular structure diagram from PubChem

CJC-1295 is a synthetic analogue of growth hormone-releasing hormone (GHRH) and a growth hormone secretagogue developed by ConjuChem Biotechnologies. It is a modified form of GHRH (1-29) with improved pharmacokinetics, especially in regard to half-life.

ByChris Riley(CFA)&Alex Evans, PharmD, MBA(PharmD, MBA)|Updated May 19, 2026

Clinically Reviewed

Reviewed by Alex Evans, PharmD, MBA · Updated May 2026

Evidence-Based

Sourced from FDA, PubMed & ClinicalTrials.gov · View sources

FDA Status

Compounding Allowed Currently on FDA bulk drug substance nomination list for compounding. GHRH analog used in combination protocols.

Evidence

Moderate Evidence

Who Is CJC-1295 Best For?

Growth hormone secretionMuscle supportRecoveryAnti-aging researchBody composition1 preclinical studyLimited human trials or strong preclinical

How CJC-1295 Works

Stimulates the pituitary gland to release growth hormone by mimicking natural GHRH signaling. The DAC version provides sustained release while the non-DAC version allows more natural pulsatile patterns.

CJC-1295 FAQ

What is CJC-1295?

CJC-1295 is a growth hormone-releasing hormone (GHRH) analog available in two forms: with DAC (Drug Affinity Complex) for extended half-life, and without DAC (MOD GRF 1-29) for more pulsatile release. It's one of the most established peptides for growth hormone research.

How does CJC-1295 work?

Is CJC-1295 legal to buy?

CJC-1295 requires a prescription from a licensed healthcare provider. It is legal to purchase with a valid prescription from authorized pharmacies.

Where can I buy CJC-1295?

CJC-1295 is available through compounding pharmacies with a valid prescription. Our directory lists verified pharmacies that compound this peptide.

What category does CJC-1295 belong to?

CJC-1295 is primarily classified as a growth hormone secretion peptide. Peptides that stimulate or support growth hormone release, including GHRH analogs, GHRPs, and direct GH compounds for muscle, recovery, and anti-aging research.

What are the research benefits of CJC-1295?

CJC-1295 has been studied for: Growth hormone secretion, Muscle support, Recovery, Anti-aging research, Body composition. Classic GHRH analog; available in compounding pharmacies.

Key Studies

30 total on PubMed17 human trials

Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects

Sackmann-Sala L, Ding J, Frohman LA et al

Growth Horm IGF Res · Growth Horm IGF ResPhase 1

CJC-1295 altered serum protein profiles including apolipoprotein A1 and transthyretin as potential GH/IGF-1 biomarkers.

CJC-1295 altered serum protein profiles including apolipoprotein A1 and transthyretin as potential GH/IGF-1 biomarkers

Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults

Teichman SL, Neale A, Lawrence B et al

J Clin Endocrinol MetabPhase 1

CJC-1295 produced sustained dose-dependent increases in GH and IGF-I levels with good safety profile

Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog

J Clin Endocrinol MetabPhase 1

CJC-1295 increased GH and IGF-I levels while preserving normal GH pulsatile secretion patterns

The study of doping market: How to produce intelligence from Internet forums

Pineau T, Schopfer A, Grossrieder L et al

Forensic Sci Int · Forensic Sci Int

CJC-1295 Compound Data

Molecular Formula

C165H269N47O46

Molecular Weight

3647.2 g/mol

IUPAC Name

(3S)-4-[[(1S)-2-[[(1S,2S)-1-[[(1S)-2-[[(1S,2R)-1-[[(1S)-4-amino-1-[[(1S)-2-[[(1S)-2-[[(1S)-1-[[(1S)-5-amino-1-[[(1S)-1-[[(1S)-1-[[(1S)-2-[[(1S)-4-amino-1-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-1-[[(1S)-5-amino-1-[[(1S)-1-[[(1S)-1-[[(1S)-4-amino-1-[[(1S)-2-[[(1S,2S)-1-[[(1S)-1-[[(1S)-2-[[(1S)-1-[[(1S)-1-carbamoyl-5-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]pentyl]carbamoyl]-4-guanidino-butyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]-2-methyl-butyl]amino]-1-(carboxymethyl)-2-oxo-ethyl]carbamoyl]-4-oxo-butyl]carbamoyl]-3-methyl-butyl]carbamoyl]-3-methyl-butyl]carbamoyl]pentyl]carbamoyl]-4-guanidino-butyl]amino]-1-methyl-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]-4-oxo-butyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]-2-methyl-propyl]carbamoyl]pentyl]carbamoyl]-4-guanidino-butyl]amino]-1-[(4-hydroxyphenyl)methyl]-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]carbamoyl]-4-oxo-butyl]carbamoyl]-2-hydroxy-propyl]amino]-1-benzyl-2-oxo-ethyl]carbamoyl]-2-methyl-butyl]amino]-1-methyl-2-oxo-ethyl]amino]-3-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-4-oxo-butanoic acid

View full compound on PubChem

CJC-1295 News

The peptide problem: Hype is outrunning the evidence - The Conversation

The Conversation · 12 days ago

Umbrella Lab Announces Documentation And Traceability Update For CJC-1295 (NO DAC)/Ipamorelin Peptide Blend - Yahoo Finance

Yahoo Finance · 5 days ago

CJC 1295 Ipamorelin Unveiled 2026: Examining the Science - GlobeNewswire

GlobeNewswire · 4 months ago

CJC-1295 and Penis Growth: What the Evidence Actually Shows - Portal CNJ

Portal CNJ · 9 days ago

RFK Jr. May Reverse a Peptide Ban He Calls “Illegal.” Former FDA Officials Say He Mischaracterized Their Work. - ProPublica

ProPublica · 1 month ago

News aggregated via Google News. Inclusion does not imply endorsement.

Medical Disclaimer: The information on this page is for educational purposes only and does not constitute medical advice. Peptide therapies have not been evaluated by the FDA for most listed indications.All prices shown are estimates based on publicly available data and may not reflect current pricing — providers and brands set their own prices and can change them at any time. Always verify pricing directly with the provider before purchasing. Consult a licensed healthcare provider before starting any peptide protocol.

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