
PT-141 Peptide Therapy
Benefits, Side Effects, Cost & Protocols
Bremelanotide (PT-141), sold under the brand name Vyleesi, is a medication used to treat hypoactive sexual desire disorder (HSDD) in premenopausal women. It is a melanocortin receptor agonist given by subcutaneous injection.
Clinically Reviewed
Reviewed by Alex Evans, PharmD, MBA · Updated May 2026
Evidence-Based
Sourced from FDA, PubMed & ClinicalTrials.gov · View sources
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How PT-141 Works
Melanocortin-4 receptor agonist that activates sexual arousal pathways in the brain, working differently from PDE5 inhibitors.
PT-141 FAQ
What is PT-141?
PT-141 (Bremelanotide) is a melanocortin peptide approved and available through compounding pharmacies for sexual dysfunction. It works through the central nervous system rather than the vascular system.
How does PT-141 work?
Melanocortin-4 receptor agonist that activates sexual arousal pathways in the brain, working differently from PDE5 inhibitors.
Is PT-141 legal to buy?
PT-141 requires a prescription from a licensed healthcare provider. It is legal to purchase with a valid prescription from authorized pharmacies.
Where can I buy PT-141?
PT-141 is available by prescription through compounding pharmacies and telehealth providers. Browse our verified provider directory to find trusted sources.
What category does PT-141 belong to?
PT-141 is primarily classified as a sexual function & libido peptide. Peptides researched for their effects on sexual function, libido, and reproductive health.
What are the research benefits of PT-141?
PT-141 has been studied for: Sexual function, Libido enhancement, Arousal support. Bremelanotide; available via compounding pharmacies for libido.
Key Studies
117 total on PubMed0Safety Profile of Bremelanotide Across the Clinical Development Program
Clayton AH, Kingsberg SA, Portman D et al
J Womens Health (Larchmt)Phase 3
Bremelanotide shows mostly mild-to-moderate adverse events; nausea most common reason for discontinuation.
Bremelanotide shows mostly mild-to-moderate adverse events; nausea most common reason for discontinuation
Prespecified and Integrated Subgroup Analyses from the RECONNECT Phase 3 Studies of Bremelanotide
Simon JA, Kingsberg SA, Portman D et al
J Womens Health (Larchmt)Phase 3
Bremelanotide improved sexual desire and reduced distress across multiple demographic and clinical subgroups.
Bremelanotide improved sexual desire and reduced distress across multiple demographic and clinical subgroups
Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials
Kingsberg SA, Clayton AH, Portman D et al
Obstet Gynecol · Obstet GynecolPhase 3
Bremelanotide significantly increased sexual desire and reduced distress in premenopausal women with hypoactive sexual desire disorder.
Bremelanotide significantly increased sexual desire and reduced distress in premenopausal women with hypoactive sexual desire disorder
Long-Term Safety and Efficacy of Bremelanotide for Hypoactive Sexual Desire Disorder
PT-141 Compound Data
PT-141 News
What Peptide Helps with Erectile Dysfunction: PT-141 and Real-World Use - stat.gov.pl
stat.gov.pl · 1 day ago
Peptide Erectile Dysfunction: Exploring PT-141 and Related Options for Men's Health - City University of Hong Kong
City University of Hong Kong · 3 days ago
Peptide for Erectile Dysfunction: What Men Need to Know About PT-141 and Similar Options - Portal CNJ
Portal CNJ · 3 days ago
Peptide for erectile dysfunction: what actually works and what to watch for - stat.gov.pl
stat.gov.pl · 1 day ago
Peptide Erectile Dysfunction: What Peptides Like PT-141 Actually Offer - Portal CNJ
Portal CNJ · 6 days ago
News aggregated via Google News. Inclusion does not imply endorsement.
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