Peptide Injections AI
PT-141 peptide therapy
Sexual Function & LibidoStrong Evidence

PT-141 Peptide Therapy

Benefits, Side Effects, Cost & Protocols

PT-141 injection vial product photoPT-141 peptide molecular structure diagram from PubChem

Bremelanotide (PT-141), sold under the brand name Vyleesi, is a medication used to treat hypoactive sexual desire disorder (HSDD) in premenopausal women. It is a melanocortin receptor agonist given by subcutaneous injection.

ByChris Riley(CFA)&Alex Evans, PharmD, MBA(PharmD, MBA)|Updated

Clinically Reviewed

Reviewed by Alex Evans, PharmD, MBA · Updated May 2026

Evidence-Based

Sourced from FDA, PubMed & ClinicalTrials.gov · View sources

FDA Status
FDA Approved June 2019 FDA approved as Vyleesi (bremelanotide) for hypoactive sexual desire disorder in premenopausal women. Also compounded.
Evidence
Strong Evidence
Category
Sexual Function & Libido

Compare PT-141 Prices

3 providers offering PT-141 — sorted lowest price first

Lowest Price
PeterMD
PT-141 Injection· 1.75mg as needed
ClinicalRx
$99
/month
Get Started
Defy Medical
PT-141 (Bremelanotide)· 1.75mg as needed
ClinicalRx
$125
/month
Get Started
Ageless Rx
PT-141· as needed
Research Use
$159
/month
Get Started

Prices shown are estimates based on publicly available data and may not reflect current pricing. Actual costs may vary by location, insurance, dosage, and formulation. Always verify directly with the provider.

How PT-141 Works

Melanocortin-4 receptor agonist that activates sexual arousal pathways in the brain, working differently from PDE5 inhibitors.

PT-141 FAQ

What is PT-141?

PT-141 (Bremelanotide) is a melanocortin peptide approved and available through compounding pharmacies for sexual dysfunction. It works through the central nervous system rather than the vascular system.

How does PT-141 work?

Melanocortin-4 receptor agonist that activates sexual arousal pathways in the brain, working differently from PDE5 inhibitors.

Is PT-141 legal to buy?

PT-141 requires a prescription from a licensed healthcare provider. It is legal to purchase with a valid prescription from authorized pharmacies.

Where can I buy PT-141?

PT-141 is available by prescription through compounding pharmacies and telehealth providers. Browse our verified provider directory to find trusted sources.

What category does PT-141 belong to?

PT-141 is primarily classified as a sexual function & libido peptide. Peptides researched for their effects on sexual function, libido, and reproductive health.

What are the research benefits of PT-141?

PT-141 has been studied for: Sexual function, Libido enhancement, Arousal support. Bremelanotide; available via compounding pharmacies for libido.

Key Studies

117 total on PubMed0

Safety Profile of Bremelanotide Across the Clinical Development Program

Clayton AH, Kingsberg SA, Portman D et al

J Womens Health (Larchmt)Phase 3

Bremelanotide shows mostly mild-to-moderate adverse events; nausea most common reason for discontinuation.

Bremelanotide shows mostly mild-to-moderate adverse events; nausea most common reason for discontinuation

Prespecified and Integrated Subgroup Analyses from the RECONNECT Phase 3 Studies of Bremelanotide

Simon JA, Kingsberg SA, Portman D et al

J Womens Health (Larchmt)Phase 3

Bremelanotide improved sexual desire and reduced distress across multiple demographic and clinical subgroups.

Bremelanotide improved sexual desire and reduced distress across multiple demographic and clinical subgroups

Bremelanotide for the Treatment of Hypoactive Sexual Desire Disorder: Two Randomized Phase 3 Trials

Kingsberg SA, Clayton AH, Portman D et al

Obstet Gynecol · Obstet GynecolPhase 3

Bremelanotide significantly increased sexual desire and reduced distress in premenopausal women with hypoactive sexual desire disorder.

Bremelanotide significantly increased sexual desire and reduced distress in premenopausal women with hypoactive sexual desire disorder

Long-Term Safety and Efficacy of Bremelanotide for Hypoactive Sexual Desire Disorder

PT-141 Compound Data

PT-141 peptide chemical structure and molecular formula from PubChem
Molecular Formula
C50H68N14O10
Molecular Weight
1025.2 g/mol
IUPAC Name
(3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-(3-guanidinopropyl)-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxylic acid
View full compound on PubChem
Medical Disclaimer: The information on this page is for educational purposes only and does not constitute medical advice. Peptide therapies have not been evaluated by the FDA for most listed indications.All prices shown are estimates based on publicly available data and may not reflect current pricing — providers and brands set their own prices and can change them at any time. Always verify pricing directly with the provider before purchasing. Consult a licensed healthcare provider before starting any peptide protocol.

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