Pnc-27 Peptide Therapy
Benefits, Side Effects, Cost & Protocols
PNC-27 is a synthetic peptide consisting of an HDM-2-binding domain attached to a membrane-active penetratin sequence. It has been studied for its ability to selectively target and destroy cancer cells by binding to HDM-2 overexpressed on tumor cell membranes, causing membrane lysis.
Clinically Reviewed
Reviewed by Alex Evans, PharmD, MBA · Updated May 2026
Evidence-Based
Sourced from FDA, PubMed & ClinicalTrials.gov · View sources
How Pnc-27 Works
Contains HDM-2 binding domain that may selectively target cells with altered p53 expression.
Pnc-27 FAQ
What is PNC-27?
PNC-27 is an experimental peptide researched for its potential selective effects on abnormal cells while sparing healthy cells.
How does PNC-27 work?
Contains HDM-2 binding domain that may selectively target cells with altered p53 expression.
Is PNC-27 legal to buy?
PNC-27 is sold as a research chemical for laboratory use only. It is not approved for human use by the FDA. Regulations vary by jurisdiction.
Where can I buy PNC-27?
PNC-27 is available as a research compound from verified online vendors. Always verify third-party testing before purchasing.
What category does PNC-27 belong to?
PNC-27 is primarily classified as a anti-aging & longevity peptide. Peptides studied for longevity, cellular senescence, telomere biology, and general anti-aging effects.
What are the research benefits of PNC-27?
PNC-27 has been studied for: Anti-cancer research, Selective cell targeting. Experimental; selective cell research.
Key Studies
25 total on PubMed18 human trialsDeath of preceding child and maternal healthcare services utilisation in Nigeria: investigation using lagged logit models
J Health Popul Nutr
Death of preceding child does not predict maternal healthcare service utilization in Nigeria after controlling for socioeconomic factors
A case-crossover analysis of out-of-hospital coronary deaths and air pollution in Rome, Italy
Forastiere F, Stafoggia M, Picciotto S et al
Am J Respir Crit Care Med
Air pollution exposure associated with 7.6% increased risk of out-of-hospital coronary death.
Air pollution exposure associated with 7.6% increased risk of out-of-hospital coronary death
Ex vivo Efficacy of Anti-Cancer Drug PNC-27 in the Treatment of Patient-Derived Epithelial Ovarian Cancer
Sarafraz-Yazdi E, Gorelick C, Wagreich AR et al
Case Series · Ann Clin Lab Sci
PNC-27 inhibits growth and is cytotoxic to patient-derived epithelial ovarian cancer cells in dose-dependent manner
Synergy between Paclitaxel and Anti-Cancer Peptide PNC-27 in the Treatment of Ovarian Cancer
Alagkiozidis I, Gorelick C, Shah T et al
Ann Clin Lab Sci · Ann Clin Lab SciAnimal
Pnc-27 News
Unauthorized injectable peptides and their potential serious health risks - College of Physicians & Surgeons of Alberta | CPSA
College of Physicians & Surgeons of Alberta | CPSA · 1 month ago
FDA Cautions Against PNC-27 Use - Oncology Nursing News
Oncology Nursing News · 113 months ago
Peptides for diagnosis and treatment of ovarian cancer - Frontiers
Frontiers · 35 months ago
Public advisory - Unauthorized injectable peptide drugs seized and sold by Canada Peptide may pose serious health risks - Yahoo! Finance Canada
Yahoo! Finance Canada · 9 months ago
PNC-27 Peptide: An Exploration of Its Potential Properties and Mechanisms - London Post
London Post · 21 months ago
News aggregated via Google News. Inclusion does not imply endorsement.
Pnc-27 Articles & Guides
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Related Peptides in Anti-Aging & Longevity
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