Anti-Aging & LongevityModerate: animal lifespan data, limited human

Epitalon Peptide Therapy

Benefits, Side Effects, Cost & Protocols

Also known as: Epithalon, Epithalamin

Epitalon peptide molecular structure diagram from PubChem

A synthetic tetrapeptide that activates telomerase, the enzyme responsible for maintaining telomere length. Studied for anti-aging and circadian rhythm regulation via melatonin pathways.

ByChris Riley(CFA)&Alex Evans, PharmD, MBA(PharmD, MBA)|Updated May 19, 2026

Clinically Reviewed

Reviewed by Alex Evans, PharmD, MBA · Updated May 2026

Evidence-Based

Sourced from FDA, PubMed & ClinicalTrials.gov · View sources

Typical Cost

$150–$350/mo

FDA Status

Research (RFK 2026 reclassification)

Evidence

Moderate: animal lifespan data, limited human

Who Is Epitalon Best For?

Anti-agingTelomere supportSleep regulation

Epitalon Compound Data

Molecular Formula

C14H22N4O9

Molecular Weight

390.35 g/mol

IUPAC Name

(4S)-4-[[(2S)-2-aminopropanoyl]amino]-5-[[(1S)-1-(carboxymethyl)-2-(carboxymethylamino)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid

View full compound on PubChem

Epitalon News

Epitalon Benefits With Peptide Expert Ryan Smith (5J35B7DX5N) - fathomjournal.org

fathomjournal.org · 3 days ago

I’m a longevity doctor — 3 peptides that can help you live longer - New York Post

New York Post · 3 months ago

Hims & Hers shares jump as FDA begins review of restricted peptide compounds - Yahoo Finance

Yahoo Finance · 1 month ago

Longevity and ‘wellness’ craze breaks untested drugs out of the lab - Financial Times

Financial Times · 2 months ago

Epitalon Peptide: Unlocking Longevity Potential - Social Life Magazine

Social Life Magazine · 5 months ago

News aggregated via Google News. Inclusion does not imply endorsement.

Epitalon Articles & Guides

In-depth articles about Epitalon and related peptide therapies.

GHK-Cu Peptide Benefits for Anti-Aging Skin: How This Copper Peptide Turns Back the Clock

GHK-Cu peptide stimulates collagen 70% better than vitamin C. Learn how this copper peptide fights wrinkles, firms skin, and resets aging at the gene level.

Read article →

Epitalon and Telomere Lengthening: What the Latest Peptide Research Reveals in 2026

Epitalon telomere lengthening peptide: what research shows about cell aging, telomerase activation, and the current evidence in longevity science.

Read article →

NAD+ Peptide Therapy for Longevity: How It Works, Key Benefits, and What to Know in 2026

NAD+ peptide therapy reverses aging at the cellular level. Learn how restoring NAD+ levels improves energy, DNA repair, and longevity with IV, injection, and oral options.

Read article →

Best Longevity Peptides for Healthspan Optimization: 7 Science-Backed Compounds Worth Knowing in 2026

Discover the top 7 longevity peptides for healthspan optimization in 2026. Evidence-based dosing, stacking protocols, and safety guidelines from clinical practice.

Read article →

Thymosin Alpha 1 vs Thymosin Beta 4 for Longevity: Which Peptide Delivers Real Anti-Aging Results?

Compare thymosin alpha 1 vs thymosin beta 4 for longevity: immune restoration vs tissue repair, evidence, safety data, and whether combining them works.

Read article →

FOXO4-DRI Senolytic Peptide: What the Latest Anti-Aging Research Reveals in 2026

FOXO4-DRI senolytic peptide selectively kills zombie cells to reverse aging. Explore 2026 research on vascular health, hormonal decline, and preclinical breakthroughs in anti-aging science.

Read article →

Explore all articles and provider comparisons:

Peptides for Anti-Aging →Peptides for Longevity →

Related Peptides in Anti-Aging & Longevity

MOTS-C

A mitochondrial-derived peptide that regulates metabolic homeostasis. Acts as an exercise mimetic, improving insulin sensitivity and fat metabolism at the cellular level.

Browse all peptides in our encyclopedia →

Medical Disclaimer: The information on this page is for educational purposes only and does not constitute medical advice. Peptide therapies have not been evaluated by the FDA for most listed indications.All prices shown are estimates based on publicly available data and may not reflect current pricing — providers and brands set their own prices and can change them at any time. Always verify pricing directly with the provider before purchasing. Consult a licensed healthcare provider before starting any peptide protocol.

Ready to explore Epitalon with a provider?

Take our 2-minute quiz to get matched with a board-certified provider specializing in Epitalon.

Take the Quiz →