Pgpipn
Peptide therapy: benefits, side effects, cost and protocols
PGPIPN is a hexapeptide derived from prolactin that has demonstrated neuroprotective properties. It protects against oxidative stress-induced neuronal damage and is studied for its potential in neurodegenerative disease prevention and cognitive preservation.
Sources: FDA / PubMed / ClinicalTrials.gov View
Spec sheet
- FDA status
- Research Only Not currently approved for human use in the US. Available as a research compound. Not eligible for compounding.
- Evidence
- Emerging Evidence
Who it's for
Who Pgpipn is usually considered for
- Anti-inflammatory potential
- Tissue repair support
- Immunomodulation
- Primarily animal or early-phase data
Mechanism
How Pgpipn works
Hexapeptide with immunomodulatory and anti-inflammatory properties that may help regulate inflammatory responses in damaged tissue.
Evidence
Key studies
6 papers on PubMed
- 01
PGPIPN, a therapeutic hexapeptide, suppressed human ovarian cancer growth by targeting BCL2
- 02
Wang W, Gu F, Wei C et al
PLoS One / Animal
- 03
PGPIPN suppressed ovarian cancer growth in vitro and in vivo by promoting apoptosis through BCL2 pathway inhibition
- 04
The milk-derived hexapeptide PGPIPN inhibits the invasion and migration of human ovarian cancer cells by regulating the expression of MTA1 and NM23H1 genes
- 05
Zhao M, Wei C, Yang X et al
In Vitro / Int J Oncol
- 06
PGPIPN hexapeptide inhibited ovarian cancer cell invasion and migration by regulating MTA1 and NM23H1 expression
- 07
Construction of an Anticancer Fusion Peptide (ACFP) Derived from Milk Proteins and an Assay of Anti-ovarian Cancer Cells in vitro
- 08
Zhou J, Yang X, Zhang W et al
In Vitro / Anticancer Agents Med Chem
- 09
ACFP fusion peptide more effectively inhibited ovarian cancer cell viability and induced apoptosis than parent peptides
FAQ
Pgpipn questions
What is PGPIPN?
PGPIPN is a therapeutic hexapeptide (Pro-Gly-Pro-Ile-Pro-Asn) researched for its immunomodulatory and anti-inflammatory properties, particularly in chronic inflammatory conditions and tissue repair.
How does PGPIPN work?
Hexapeptide with immunomodulatory and anti-inflammatory properties that may help regulate inflammatory responses in damaged tissue.
Is PGPIPN legal to buy?
PGPIPN is sold as a research chemical for laboratory use only. It is not approved for human use by the FDA. Regulations vary by jurisdiction.
Where can I buy PGPIPN?
PGPIPN is available as a research compound from verified online vendors. Always verify third-party testing before purchasing.
What category does PGPIPN belong to?
PGPIPN is primarily classified as a tissue repair & healing peptide. Peptides studied for their potential in wound healing, tendon/ligament repair, gut healing, and general tissue regeneration.
What are the research benefits of PGPIPN?
PGPIPN has been studied for: Anti-inflammatory potential, Tissue repair support, Immunomodulation. Emerging research peptide; limited clinical data.
News
Pgpipn in the news
News aggregated via Google News. Inclusion does not imply endorsement.
Considering Pgpipn?
The 2-minute quiz matches you with licensed providers who offer it. A clinician decides if it fits.