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Epithalon peptide therapy
Anti-Aging & LongevityModerate Evidence

Epithalon Peptide Therapy

Benefits, Side Effects, Cost & Protocols

Epithalon peptide molecular structure diagram from PubChem

Epitalon (Epithalon) is a synthetic tetrapeptide and telomerase activator identified as the putative active component of a bovine pineal gland extract known as epithalamin. It has been studied for potential anti-aging effects through telomere elongation.

ByChris Riley(CFA)&Alex Evans, PharmD, MBA(PharmD, MBA)|Updated

Clinically Reviewed

Reviewed by Alex Evans, PharmD, MBA · Updated May 2026

Evidence-Based

Sourced from FDA, PubMed & ClinicalTrials.gov · View sources

FDA Status
Research Only Not currently approved for human use in the US. Available as a research compound. Not eligible for compounding.
Evidence
Moderate Evidence
Category
Anti-Aging & Longevity

How Epithalon Works

May activate telomerase enzyme, potentially lengthening telomeres and influencing cellular senescence processes.

Epithalon FAQ

What is EPITHALON?

Epithalon (Epitalon) is a synthetic tetrapeptide researched for its potential effects on telomerase activation and cellular aging. It's based on the naturally occurring epithalamin from the pineal gland.

How does EPITHALON work?

May activate telomerase enzyme, potentially lengthening telomeres and influencing cellular senescence processes.

Is EPITHALON legal to buy?

EPITHALON is sold as a research chemical for laboratory use only. It is not approved for human use by the FDA. Regulations vary by jurisdiction.

Where can I buy EPITHALON?

EPITHALON is available as a research compound from verified online vendors. Always verify third-party testing before purchasing.

What category does EPITHALON belong to?

EPITHALON is primarily classified as a anti-aging & longevity peptide. Peptides studied for longevity, cellular senescence, telomere biology, and general anti-aging effects.

What are the research benefits of EPITHALON?

EPITHALON has been studied for: Telomerase activation, Anti-aging research, Cellular longevity. Telomerase activation research; popular in longevity circles.

Key Studies

126 total on PubMed0

[The effect of heavy metal ions and peptide bioregulators on the expression of chromosome fragile sites in the individuals of different age groups and breast cancer patients]

Case Series · Georgian Med News

Epithalon and Livagen reduced heavy metal-induced chromosome fragility in young and aged individuals

[Functional regulation of genome with peptide bioregulators by hypertrophic cardiomyopathy (by patients and relatives)]

Dzhokhadze TA, Buadze TZh, Gaĭozishvili MN et al

Case Series · Georgian Med News

Epithalon reduced chromosomal instability in hypertrophic cardiomyopathy patients

[Genome instability in pulmonary tuberculosis before and after treatment]

Dzhokhadze TA, Buadze TZh, Rubanov KD et al

Case Series · Georgian Med News

Epitalon showed protective effect against chromosome aberrations in tuberculosis patients post-treatment

Effects of short peptides on lymphocyte chromatin in senile subjects

Case Series · Bull Exp Biol Med

Short peptides activated ribosome genes and decondensed chromatin in elderly subjects

Epithalon Compound Data

Epithalon peptide chemical structure and molecular formula from PubChem
Molecular Formula
C14H22N4O9
Molecular Weight
390.35 g/mol
IUPAC Name
(4S)-4-[[(2S)-2-aminopropanoyl]amino]-5-[[(1S)-1-(carboxymethyl)-2-(carboxymethylamino)-2-oxo-ethyl]amino]-5-oxo-pentanoic acid
View full compound on PubChem

Epithalon Articles & Guides

In-depth articles about Epithalon and related peptide therapies.

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Epitalon and Telomere Lengthening: What the Latest Peptide Research Reveals in 2026

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Medical Disclaimer: The information on this page is for educational purposes only and does not constitute medical advice. Peptide therapies have not been evaluated by the FDA for most listed indications.All prices shown are estimates based on publicly available data and may not reflect current pricing — providers and brands set their own prices and can change them at any time. Always verify pricing directly with the provider before purchasing. Consult a licensed healthcare provider before starting any peptide protocol.

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