Triptorelin Peptide Therapy

Ten-year update of HOBOE phase III trial comparing triptorelin plus either tamoxifen or letrozole or zoledronic acid + letrozole in premenopausal hormone receptor-positive early breast cancer patients

Gravina A, Gargiulo P, De Laurentiis M et al

ESMO OpenPhase 3

9.2 years median follow-up

Triptorelin plus letrozole or zoledronic acid plus letrozole improved disease-free survival over tamoxifen in premenopausal HR+ early breast cancer

Ovulation triggering with hCG alone, GnRH agonist alone or in combination? A randomized controlled trial in advanced-age women undergoing IVF/ICSI cycles

Zhou C, Yang X, Wang Y et al

Hum Reprod · Hum ReprodPhase 3

Dual GnRHa+hCG trigger improves embryo quality and frozen embryo live birth rates vs single GnRHa in advanced-age women

Short-term Androgen Deprivation Therapy and High-dose Radiotherapy in Intermediate- and High-risk Localized Prostate Cancer: Results from the GETUG 14 Randomized Phase 3 Trial

Demogeot N, Sargos P, Salleron J et al

Eur Urol · Eur UrolPhase 3

84 months median follow-up

Short-term ADT with high-dose RT improved 5-year DFS (84% vs 76%) and reduced biochemical failure in intermediate/high-risk prostate cancer

Assessment of Two Formulations of Triptorelin in Chinese Patients with Endometriosis: A Phase 3, Randomized Controlled Trial