Melanotan Ii Peptide Therapy
Benefits, Side Effects, Cost & Protocols
Melanotan II is a synthetic analogue of the peptide hormone alpha-melanocyte-stimulating hormone (alpha-MSH) that stimulates melanogenesis to facilitate tanning. It has also been studied for its effects on sexual arousal and appetite suppression.
Clinically Reviewed
Reviewed by Alex Evans, PharmD, MBA · Updated May 2026
Evidence-Based
Sourced from FDA, PubMed & ClinicalTrials.gov · View sources
Who Is Melanotan Ii Best For?
How Melanotan Ii Works
Melanocortin receptor agonist that stimulates melanogenesis for tanning and activates pathways involved in sexual arousal.
Melanotan Ii FAQ
What is MELANOTAN II?
Melanotan II is a synthetic melanocortin peptide researched for its tanning and libido-enhancing effects. It stimulates melanin production and has notable sexual function effects.
How does MELANOTAN II work?
Melanocortin receptor agonist that stimulates melanogenesis for tanning and activates pathways involved in sexual arousal.
Is MELANOTAN II legal to buy?
MELANOTAN II is sold as a research chemical for laboratory use only. It is not approved for human use by the FDA. Regulations vary by jurisdiction.
Where can I buy MELANOTAN II?
MELANOTAN II is available as a research compound from verified online vendors. Always verify third-party testing before purchasing.
What category does MELANOTAN II belong to?
MELANOTAN II is primarily classified as a skin, hair & cosmetic peptide. Peptides studied for cosmetic applications including skin rejuvenation, collagen production, tanning, hair growth, and anti-wrinkle effects.
What are the research benefits of MELANOTAN II?
MELANOTAN II has been studied for: Tanning without sun exposure, Libido enhancement, Skin darkening. Tanning + libido effects; popular cosmetic/lifestyle peptide.
Key Studies
242 total on PubMed74 human trialsMelanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II
Wessells H, Levine N, Hadley ME et al
Int J Impot ResPhase 2
Melanotan II induced penile erection in 85% of men with erectile dysfunction and increased sexual desire
Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction
Wessells H, Gralnek D, Dorr R et al
UrologyRCT
6 hours per session
Melanotan II induced erections in 63% of injections and increased sexual desire versus placebo
Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study
Dorr RT, Lines R, Levine N et al
Life Sci · Life SciPhase 1
Melanotan II produced dose-dependent skin pigmentation, penile erections, and mild adverse effects in healthy volunteers.
Melanotan II produced dose-dependent skin pigmentation, penile erections, and mild adverse effects in healthy volunteers
Melanotan II User Experience: A Qualitative Study of Online Discussion Forums
Dermatology
Melanotan Ii Compound Data
Melanotan Ii News
Inside the ‘Barbie Drug’ Tanning Trend - WWD
WWD · 13 days ago
The peptide revolution: inside the injectables industry - The Times
The Times · 5 days ago
Melanotan II 'Barbie drug' tanning peptide raises safety concerns - MSN
MSN · 11 days ago
Melanotan and Erectile Dysfunction: What the Evidence Shows - Portal CNJ
Portal CNJ · 6 days ago
The FDA May Reverse a Ban on Several Peptides With Potential Beauty Benefits. What Does That Mean, Exactly? - Allure
Allure · 7 days ago
News aggregated via Google News. Inclusion does not imply endorsement.
Ready to explore Melanotan Ii with a provider?
Take our 2-minute quiz to get matched with a board-certified provider specializing in Melanotan Ii.
Take the Quiz →