GHK-Cu
Peptide therapy: benefits, side effects, cost and protocols
GHK-Cu (copper peptide) is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine, first isolated from human plasma. It has been studied for its roles in wound healing, tissue remodeling, skin regeneration, and anti-inflammatory activity.
Sources: FDA / PubMed / ClinicalTrials.gov View
Spec sheet
- Lowest listed
- $149/mo
- FDA status
- Banned from Compounding March 2024 Removed from compounding nomination list. Available as topical cosmetic ingredient but not for injection.
- Evidence
- Moderate Evidence
Price sheet
GHK-Cu prices, lowest first
1 listing.
We may earn a commission at no extra cost to you. Disclosure
| Provider | Per month | Link |
|---|---|---|
Ageless Rx GHK-Cu Peptide / topical Research Use | $149 | Visit |
Prices shown are estimates based on publicly available data and may not reflect current pricing. Actual costs may vary by location, insurance, dosage, and formulation. Always verify directly with the provider.
Mechanism
How GHK-Cu works
Copper-bound tripeptide that stimulates collagen and elastin production, promotes wound healing, and may have anti-inflammatory and antioxidant effects.
Evidence
Key studies
182 papers on PubMed / 65 human trials
- 01
Effects of topical copper tripeptide complex on CO2 laser-resurfaced skin
- 02
Miller TR, Wagner JD, Baack BR et al
Arch Facial Plast Surg / Arch Facial Plast Surg / RCT
GHK-Cu offered no significant reduction in erythema or wrinkles but improved patient satisfaction.
- 03
GHK-Cu offered no significant reduction in erythema or wrinkles but improved patient satisfaction
- 04
Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction
- 05
Fu SC, Cheuk YC, Chiu WY et al
J Orthop Res / Animal
GHK-Cu improved knee laxity at 6 weeks post-ACLR in rats but effects did not persist.
- 06
GHK-Cu improved knee laxity at 6 weeks post-ACLR in rats but effects did not persist
- 07
Glycyl-l-histidyl-l-lysine-Cu(2+) rescues cigarette smoking-induced skeletal muscle dysfunction via a sirtuin 1-dependent pathway
- 08
Deng M, Zhang Q, Yan L et al
J Cachexia Sarcopenia Muscle / Animal
- 09
GHK-Cu rescues cigarette smoking-induced skeletal muscle dysfunction via SIRT1 activation in mice and human cell models
- 10
Golgi-targeted copper delivery strategy via enhancing copper-dependent proteins' activity for fascia regeneration
Compound
GHK-Cu compound data
- Formula
- C14H21CuN6O4-
- Mol. weight
- 400.90 g/mol
- PubChem CID
- 139035031 ↗
- IUPAC
- copper (2S)-6-amino-2-[[(2S)-2-(2-azanidylacetyl)azanidyl-3-(1H-imidazol-4-yl)propanoyl]amino]hexanoate
FAQ
GHK-Cu questions
What is GHK-CU?
GHK-Cu (Copper Peptide) is one of the most researched peptides for skin rejuvenation, wound healing, and collagen production. The copper complex enhances its biological activity.
How does GHK-CU work?
Copper-bound tripeptide that stimulates collagen and elastin production, promotes wound healing, and may have anti-inflammatory and antioxidant effects.
Is GHK-CU legal to buy?
GHK-CU is sold as a research chemical for laboratory use only. It is not approved for human use by the FDA. Regulations vary by jurisdiction.
Where can I buy GHK-CU?
GHK-CU is available as a research compound from verified online vendors. Always verify third-party testing before purchasing.
What category does GHK-CU belong to?
GHK-CU is primarily classified as a tissue repair & healing peptide. Peptides studied for their potential in wound healing, tendon/ligament repair, gut healing, and general tissue regeneration.
What are the research benefits of GHK-CU?
GHK-CU has been studied for: Collagen production, Wound healing, Skin rejuvenation, Anti-aging skin research, Hair follicle support. Collagen/wound healing star; popular for cosmetic and healing research.
News
GHK-Cu in the news
The copper peptide trend has gone from creams to injections — ahead of the science - NPR
NPR / 1 month ago
AgelessRx Launches GHK-Cu Copper Peptide Cream for Clinician-Guided Skin Longevity - Yahoo Finance
Yahoo Finance / 3 days ago
GHK-Cu: A Multifunctional Copper-Binding Peptide - Daily Leader
Daily Leader / 2 days ago
I Tried a $350 Compounded Copper Peptide Cream. Was It Better Than OTC? - Allure
Allure / 1 month ago
Celebs Are Injecting Copper to Look Younger. What Could Go Wrong? - The Hollywood Reporter
The Hollywood Reporter / 2 months ago
News aggregated via Google News. Inclusion does not imply endorsement.
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