
GHK (glycyl-L-histidyl-L-lysine) is a naturally occurring tripeptide found in human plasma, saliva, and urine. It has been extensively studied for its roles in wound healing, tissue remodeling, collagen synthesis, and anti-inflammatory activity. Levels decline significantly with age.
Clinically Reviewed
Reviewed by Alex Evans, PharmD, MBA · Updated July 2026
Evidence-Based
Sourced from FDA, PubMed & ClinicalTrials.gov · View sources
Who Is Ghk Best For?
How Ghk Works
Modulates gene expression related to tissue remodeling, collagen synthesis, and wound healing.
Ghk FAQ
What is GHK?
GHK is a naturally occurring tripeptide that serves as the base form of GHK-Cu. It's researched for wound healing and tissue repair properties.
How does GHK work?
Modulates gene expression related to tissue remodeling, collagen synthesis, and wound healing.
Is GHK legal to buy?
GHK is sold as a research chemical for laboratory use only. It is not approved for human use by the FDA. Regulations vary by jurisdiction.
Where can I buy GHK?
GHK is available as a research compound from verified online vendors. Always verify third-party testing before purchasing.
What category does GHK belong to?
GHK is primarily classified as a tissue repair & healing peptide. Peptides studied for their potential in wound healing, tendon/ligament repair, gut healing, and general tissue regeneration.
What are the research benefits of GHK?
GHK has been studied for: Tissue repair, Wound healing, Skin health. Base form of GHK-Cu copper peptide.
Key Studies
459 total on PubMed205 human trialsGeneration Healthy Kids: Protocol for a cluster-randomized controlled trial of a multi-component and multi-setting intervention to promote healthy weight and wellbeing in 6-11-year-old children in Denmark
Thomsen LT, Schmidt-Persson J, Damsgaard CT et al
PLoS OneRCT
Multi-component intervention targeting diet, activity, and sleep reduces fat mass in children
Clinical manifestations of IgE hypogammaglobulinemia
Smith JK, Krishnaswamy GH, Dykes R et al
Ann Allergy Asthma Immunol · Ann Allergy Asthma Immunol
IgE-deficient patients have higher prevalence of autoimmune disease and nonallergic airway disease
Significant improvement in crow's feet after treatment with Jet-M and a mixed solution of copper-GHK, oligo-hyaluronic acid, rhodiolar extract, tranexamic acid, and β-glucan (GHR formulation)
Byun SY, Chae JB, Na JI et al
Case Series · J Cosmet Laser Ther
Crow's feet wrinkles greatly decreased with increased collagen and elastic fiber production.
Crow's feet wrinkles greatly decreased with increased collagen and elastic fiber production
Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction
Ghk Compound Data
Ghk News
Evolv launches oral hair growth supplement powered by GHK-Cu-inspired peptide - Chain Drug Review
Chain Drug Review · today
Evolv Launches Evolv Grow, a Next-Generation Oral GHK-Cu Hair Growth Supplement for Men and Women Powered by EV2 Peptide™ - PR Newswire
PR Newswire · today
FDA scientists flag concerns with peptides, the trendy molecules RFK Jr. supports - NPR
NPR · 2 days ago
The anti-aging peptide everyone is suddenly talking about - USA Today
USA Today · 19 days ago
It’s the latest wonder ingredient promising firmer skin – the 6 best copper peptide serums - Get the Gloss
Get the Gloss · 7 days ago
News aggregated via Google News. Inclusion does not imply endorsement.
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