Ghk
Peptide therapy: benefits, side effects, cost and protocols
GHK (glycyl-L-histidyl-L-lysine) is a naturally occurring tripeptide found in human plasma, saliva, and urine. It has been extensively studied for its roles in wound healing, tissue remodeling, collagen synthesis, and anti-inflammatory activity. Levels decline significantly with age.
Sources: FDA / PubMed / ClinicalTrials.gov View
Spec sheet
- FDA status
- Research Only Not currently approved for human use in the US. Available as a research compound. Not eligible for compounding.
- Evidence
- Moderate Evidence
Who it's for
Who Ghk is usually considered for
- Tissue repair
- Wound healing
- Skin health
- Limited human trials or strong preclinical
Mechanism
How Ghk works
Modulates gene expression related to tissue remodeling, collagen synthesis, and wound healing.
Evidence
Key studies
481 papers on PubMed / 223 human trials
- 01
Generation Healthy Kids: Protocol for a cluster-randomized controlled trial of a multi-component and multi-setting intervention to promote healthy weight and wellbeing in 6-11-year-old children in Denmark
- 02
Thomsen LT, Schmidt-Persson J, Damsgaard CT et al
PLoS One / RCT
- 03
Multi-component intervention targeting diet, activity, and sleep reduces fat mass in children
- 04
Clinical manifestations of IgE hypogammaglobulinemia
- 05
Smith JK, Krishnaswamy GH, Dykes R et al
Ann Allergy Asthma Immunol / Ann Allergy Asthma Immunol
- 06
IgE-deficient patients have higher prevalence of autoimmune disease and nonallergic airway disease
- 07
Significant improvement in crow's feet after treatment with Jet-M and a mixed solution of copper-GHK, oligo-hyaluronic acid, rhodiolar extract, tranexamic acid, and β-glucan (GHR formulation)
- 08
Byun SY, Chae JB, Na JI et al
Case Series / J Cosmet Laser Ther
Crow's feet wrinkles greatly decreased with increased collagen and elastic fiber production.
- 09
Crow's feet wrinkles greatly decreased with increased collagen and elastic fiber production
- 10
Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction
Compound
Ghk compound data
- Formula
- C14H24N6O4
- Mol. weight
- 340.38 g/mol
- PubChem CID
- 73587 ↗
- IUPAC
- (2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid
FAQ
Ghk questions
What is GHK?
GHK is a naturally occurring tripeptide that serves as the base form of GHK-Cu. It's researched for wound healing and tissue repair properties.
How does GHK work?
Modulates gene expression related to tissue remodeling, collagen synthesis, and wound healing.
Is GHK legal to buy?
GHK is sold as a research chemical for laboratory use only. It is not approved for human use by the FDA. Regulations vary by jurisdiction.
Where can I buy GHK?
GHK is available as a research compound from verified online vendors. Always verify third-party testing before purchasing.
What category does GHK belong to?
GHK is primarily classified as a tissue repair & healing peptide. Peptides studied for their potential in wound healing, tendon/ligament repair, gut healing, and general tissue regeneration.
What are the research benefits of GHK?
GHK has been studied for: Tissue repair, Wound healing, Skin health. Base form of GHK-Cu copper peptide.
News
Ghk in the news
The copper peptide trend has gone from creams to injections — ahead of the science - NPR
NPR / 1 month ago
AgelessRx Launches GHK-Cu Copper Peptide Cream for Clinician-Guided Skin Longevity - Yahoo Finance
Yahoo Finance / 3 days ago
GHK-Cu: A Multifunctional Copper-Binding Peptide - Daily Leader
Daily Leader / 2 days ago
The Tri-Peptide Synergy in Molecular Inquiry: BPC-157, TB-500 and GHK-Cu (GLOW Blend) - Star Local Media
Star Local Media / 2 days ago
I Tried a $350 Compounded Copper Peptide Cream. Was It Better Than OTC? - Allure
Allure / 1 month ago
News aggregated via Google News. Inclusion does not imply endorsement.
Considering Ghk?
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