Tissue Repair & HealingModerate Evidence

Ghk Peptide Therapy

Benefits, Side Effects, Cost & Protocols

Ghk peptide molecular structure diagram from PubChem

GHK (glycyl-L-histidyl-L-lysine) is a naturally occurring tripeptide found in human plasma, saliva, and urine. It has been extensively studied for its roles in wound healing, tissue remodeling, collagen synthesis, and anti-inflammatory activity. Levels decline significantly with age.

ByChris Riley(CFA)&Alex Evans, PharmD, MBA(PharmD, MBA)|Updated October 8, 2026

Clinically Reviewed

Reviewed by Alex Evans, PharmD, MBA · Updated October 2026

Evidence-Based

Sourced from FDA, PubMed & ClinicalTrials.gov · View sources

FDA Status

Research Only Not currently approved for human use in the US. Available as a research compound. Not eligible for compounding.

Evidence

Moderate Evidence

Who Is Ghk Best For?

Tissue repairWound healingSkin healthLimited human trials or strong preclinical

How Ghk Works

Modulates gene expression related to tissue remodeling, collagen synthesis, and wound healing.

Ghk FAQ

What is GHK?

GHK is a naturally occurring tripeptide that serves as the base form of GHK-Cu. It's researched for wound healing and tissue repair properties.

How does GHK work?

Modulates gene expression related to tissue remodeling, collagen synthesis, and wound healing.

Is GHK legal to buy?

GHK is sold as a research chemical for laboratory use only. It is not approved for human use by the FDA. Regulations vary by jurisdiction.

Where can I buy GHK?

GHK is available as a research compound from verified online vendors. Always verify third-party testing before purchasing.

What category does GHK belong to?

GHK is primarily classified as a tissue repair & healing peptide. Peptides studied for their potential in wound healing, tendon/ligament repair, gut healing, and general tissue regeneration.

What are the research benefits of GHK?

GHK has been studied for: Tissue repair, Wound healing, Skin health. Base form of GHK-Cu copper peptide.

Key Studies

480 total on PubMed0

Generation Healthy Kids: Protocol for a cluster-randomized controlled trial of a multi-component and multi-setting intervention to promote healthy weight and wellbeing in 6-11-year-old children in Denmark

Thomsen LT, Schmidt-Persson J, Damsgaard CT et al

PLoS OneRCT

Multi-component intervention targeting diet, activity, and sleep reduces fat mass in children

Clinical manifestations of IgE hypogammaglobulinemia

Smith JK, Krishnaswamy GH, Dykes R et al

Ann Allergy Asthma Immunol · Ann Allergy Asthma Immunol

IgE-deficient patients have higher prevalence of autoimmune disease and nonallergic airway disease

Significant improvement in crow's feet after treatment with Jet-M and a mixed solution of copper-GHK, oligo-hyaluronic acid, rhodiolar extract, tranexamic acid, and β-glucan (GHR formulation)

Byun SY, Chae JB, Na JI et al

Case Series · J Cosmet Laser Ther

Crow's feet wrinkles greatly decreased with increased collagen and elastic fiber production.

Crow's feet wrinkles greatly decreased with increased collagen and elastic fiber production

Tripeptide-copper complex GHK-Cu (II) transiently improved healing outcome in a rat model of ACL reconstruction

Ghk Compound Data

Molecular Formula

C14H24N6O4

Molecular Weight

340.38 g/mol

IUPAC Name

(2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid

View full compound on PubChem

Ghk News

The copper peptide trend has gone from creams to injections — ahead of the science - NPR

NPR · 1 month ago

Synthesis Peptides Reviews 2026: Your Next Research Supplier? GHK-Cu Pricing, Volume Discounts, and COA Details - Newswire

Newswire · 5 days ago

Nox Peptides Announces Expanded Research Focus on BPC-157 and GHK-Cu in Canada - Yahoo Finance

Yahoo Finance · 6 days ago

Nox Peptides Announces Launch of GHK-Cu and Wolverine Stack for Canadian Research Market - Lelezard

Lelezard · 1 day ago

I Tried a $350 Compounded Copper Peptide Cream. Was It Better Than OTC? - Allure

Allure · 28 days ago

News aggregated via Google News. Inclusion does not imply endorsement.

Medical Disclaimer: The information on this page is for educational purposes only and does not constitute medical advice. Peptide therapies have not been evaluated by the FDA for most listed indications.All prices shown are estimates based on publicly available data and may not reflect current pricing — providers and brands set their own prices and can change them at any time. Always verify pricing directly with the provider before purchasing. Consult a licensed healthcare provider before starting any peptide protocol.

Ready to explore Ghk with a provider?

Take our 2-minute quiz to get matched with a board-certified provider specializing in Ghk.

Take the Quiz →